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Hong Lim Selected Research

KR-31543

2/2004In vitro metabolism of a new neuroprotective agent, KR-31543 in the human liver microsomes: identification of human cytochrome P450.
1/2003Dose-independent pharmacokinetics of a new neuroprotective agent for ischemia-reperfusion damage, KR-31543, after intravenous and oral administration to rats: hepatic and intestinal first-pass effects.
10/2002Metabolism of a new neuroprotective agent for ischemia-reperfusion damage, KR-31543 in the rat using liquid chromatography/electrospray mass spectrometry.

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Hong Lim Research Topics

Disease

7Reperfusion Injury
04/2004 - 10/2002
7Ischemia
03/2004 - 04/2002
2Hypoxia (Hypoxemia)
12/2004 - 12/2004
2Infarction (Infarctions)
03/2004 - 04/2002
1Acquired Immunodeficiency Syndrome (AIDS)
10/2005
1Thrombosis (Thrombus)
04/2004
1Brain Ischemia (Cerebral Ischemia)
03/2004
1Brain Injuries (Brain Injury)
03/2004
1Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome)
03/2004
1Edema (Dropsy)
03/2004
1Diabetic Neuropathies (Diabetic Neuropathy)
05/2003
1Erectile Dysfunction
01/2003
1Cerebral Infarction
04/2002

Drug/Important Bio-Agent (IBA)

7N''- cyano- N- (6- amino- 3,4- dihydro- 3- hydroxy- 2- methyl- 2- dimethoxymethyl- 2H- benzopyran- 4- yl)- N'- benzylguanidineIBA
12/2004 - 04/2002
6Neuroprotective AgentsIBA
04/2004 - 10/2002
5BenzopyransIBA
12/2004 - 04/2002
3KR-31543IBA
02/2004 - 10/2002
2KATP ChannelsIBA
12/2004 - 12/2004
2AntioxidantsIBA
03/2004 - 04/2002
2benzylguanidineIBA
03/2004 - 04/2002
1DBM 2198IBA
10/2005
1TransferasesIBA
12/2004
1Protein Kinase C-epsilonIBA
12/2004
1Protein Isoforms (Isoforms)IBA
12/2004
1Uridine Triphosphate (UTP)IBA
12/2004
1p38 Mitogen-Activated Protein KinasesIBA
12/2004
1BuffersIBA
12/2004
1Pharmaceutical PreparationsIBA
04/2004
1Glutathione (Reduced Glutathione)IBA
03/2004
1CytochromesIBA
10/2003
1SR 4668IBA
05/2003
1Sildenafil Citrate (Viagra)FDA Link
01/2003
1KR-31612IBA
10/2002

Therapy/Procedure

3Oral Administration
04/2004 - 01/2003
1Vena Cava Filters (Inferior Vena Cava Filter)
04/2004